Proposal for a Concise Method to Explore Reasonable Cutoffs from Clinical Databases by Exploiting Serial Testing

• 발행기관: 한국자료분석학회
• 저자명: Shuhei Fujita Makoto Tomita Sungho Moon Hirokuni Arai
• 간행물 정보: 『Journal of The Korean Data Analysis Society (JKDAS)』Vol.15 No.3, 1139~1149쪽, 전체 11쪽
• 주제분류: 자연과학 > 통계학
• 파일형태: PDF
• 발행일자: 2013.06.30

영문 초록

In clinical practice, medical professionals are likely to rely on various scoring systems and their suggested cutoffs to evaluate the severity of disease or the risk to patients and the key of scoring system and database is the reliable cutoff. We herein report a novel and concise method to calculate the significant cutoff by exploiting serial testing with the result of tricuspid valve surgery. In tricuspid surgery, tricuspid annuloplication with annuloplasty ring has been common procedure to fix tricuspid regurgitation, but the optimal ring size has not been determined. We defined the new index TARI (Tricuspid Annuloplasty Ring size Index), which normalizes the ring size by body surface area. We tested all cutoff candidates of TARI sequentially and confirmed which value was the most significant cutoff to achieve the best result. Our method would be simple and be widely applicable for any dataset that has negative or positive correlations.

목차

1. Introduction

2. Dataset

3. Threshold calculation by exploiting serial t-test

4. To assess the reliability of the estimated threshold

5. The table of recommended tricuspid value annuloplasty ring sizes for each BSA based on TARI

6. Discussion

References

키워드

cutoff serial testing clinical database tricuspid regurgitation