rvH1N1 Neuraminidase Inhibitory Activities of Phenolics from Perilla frutescens (L.) and Comparison of Their Contents Among Cultivars and Germplasms

• 발행기관: 한국작물학회
• 저자명: Tae Joung Ha Myoung-Hee Lee Jung-In Kim Suk-Bok Pae Eunyoung Oh Sungup Kim Sovetgul Asekova Doyeon Kwak
• 간행물 정보: 『한국작물학회 학술발표대회 논문집』2018년도 춘계학술대회, 188~188쪽, 전체 1쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2018.04.19

영문 초록

Pharmacological strategies for dealing with influenza pandemic is now based on antiviral drugs, in which neuraminidase (NA) inhibitors are the most important. There is no doubt that the agricultural production is the most important of Perilla frutescens. In comparison with the production, the phytopharmacology is not fully investigated in biological activity, although it is widely used as traditional Chinese medicines for various diseases, such as cold due to wind-cold, headache and cough. To the best of our knowledge, the investigation regarding NA inhibition of this plant has still not been reported. This prompted us to examine major four phenolic compounds isolated from Perilla to gain new insights into their NA inhibitory action on a molecular basis. We also quantified the content of these compounds of Korean perilla germplasms and cultivars.