Stability of Separated ACE Inhibitory Peptides under Condition of Various pH, Temperature, Gastric Digestion (In Vitro)

• 영문명: Stability of Separated ACE Inhibitory Peptides under Condition of Various pH, Temperature, Gastric Digestion (In Vitro)
• 발행기관: 한국축산식품학회
• 저자명: Jang, Ae-Ra Lee, Moo-Ha
• 간행물 정보: 『학술대회논문집』2005년도 제36차 추계 학술발표대회, 329~333쪽, 전체 5쪽
• 주제분류: 농수해양 > 식품과학
• 파일형태: PDF
• 발행일자: 2005.10.31

영문 초록

ACE inhibition activity of peptides was measured after 2 months of storage at 4℃ under condition of pH 6.0, 6.5, 7.0, 7.5, 8.0. and the ACE inhibitory activity were changed only slightly. After 2 months of chilled storage (4℃ ), no dramatic change and significance was found. This indicates that acidic, neutral, weak alkali conditions did not affect ACE inhibitory activity of those peptides. Among peptide 1134, 1152, and 1155, peptides from thermolysin + protease A hydrolysates, inhibition activity of peptide 1134 and 1152 was decreased significantly at 60℃ , however, they showed stable inhibition activity from 70℃ to 100℃ (P<0.001). Also, chromatogram of peptide 1134, 1152, and 1155 was shown that retention time of peptide of 60℃ was not correspond to the retention time of the rest of peptides. This indicated that temperature may change the inhibitory activity and profile of peptides.

목차

Introduction

Materials and Methods

Results and Discussion

Summary