게이트심장혈액풀스캔과 게이트심장혈액풀 SPECT로 측정한 심박출계수의 심초음파와의 비교 연구

• 영문명: Comparison of the Ejection Fraction Between Gated Blood Pool, Gated Blood Pool SPECT and Echocardiography
• 발행기관: 대한핵의학기술학회
• 저자명: 정지욱(Ji Uk Jeong) 이효영(Hyo Yeong Lee) 윤종준(Jong-Jun Yun) 이화진(Hwa-jin Lee) 이무석(Moo-Seok Lee) 송현석(Hyeon-Seok Song) 박세윤(Se-Yun Park) 김재환(Jae-Hwan Kim)
• 간행물 정보: 『핵의학기술』Vol.14 No.2, 150~154쪽, 전체 5쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2010.10.30

영문 초록

Purpose: Ejection fraction (EF) is one of the most important factors that evaluate heart function. Recently, according to echocardiography and myocardial perfusion SPECT, the number of gated blood pool scan (planar GBP) is declining. Measurement of left ventricular ejection fraction using gated blood pool SPECT (GBPS) is known as relatively correspond with echocardiography. We compared EF derived from plnar GBP, GBPS and echocadiography using modified simpson method to determine the accuracy. Materials and Methods: From January 2007 to June 2010, planar GBP and GBPS were performed on 34 patients who admitted to Pusan National University Hospital (men 23, women 11, mean age 52.6±27.2). Each patient was injected with ⁹⁹ᵐTcO₄-of 20 mCi after pyrophosphate injection and then scanned using both planar GBP and GBPS techniques. For image analysis, we use ADAC Laboratories, Ver. 4.20 software. The result analyzed was processed by SPSS 17.0 Win statistic program and statistical method applied in data analysis is one-way anova, Tukey’s post hoc test, pearson correlation test. Results: One-way anova test show no significant difference (planar GBP 56.3±13.9%; GBPS 60.4±16.0%; echocardiography 59.1±14.4%, p=0.486, p>0.05). Tukey’s post hoc test show no significant difference (planar GBP-echocardiography p=0.697; GBPS-echocardiography p=0.928; planar GBP-GBPS p=0.469, p>0.05). Values for EF obtained with planar GBP and GBPS correlated well with those obtained with echocardiography (planar-echocardiography r=0.697; GBPS-echocardiography r=0.928; planar GBP-GBPS r=0.469). Conclusion: The problems of accuracy and reproducibility for planar GBP still remain. But planar GBP is a safe and non-invasive method. In addition, planar GBP is useful to evaluate patient with low resolution echocardiography images. GBPS is not appicated clinically. but GBPS can be obtain various left ventricular functional parameters. planar GBP, GBPS and echocardiography show a good correlation between each other. Therefore, planar GBP and GBPS are useful for evaluating left ventricular ejection fraction.

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실험재료 및 방법

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키워드

Gated blood pool scan (planar GBP) Gated blood pool SPECT (GBPS) Ejection fraction (EF) Echocardiography