유방암 환자의 Positron Emission Mammography에서의 유용성에 관한 연구

• 영문명: A Study on Availability about Positron Emission Mammography of Breast Cancer
• 발행기관: 대한핵의학기술학회
• 저자명: 김승정(Seung Jeong Kim) 김재일(Jae Il Kim) 김진의(Jin Eui Kim) 김현주(Hyun Joo Kim)
• 간행물 정보: 『핵의학기술』Vol.14 No.2, 60~64쪽, 전체 5쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2010.10.30

영문 초록

Purpose: Until now the general study for breast cancer patient has been mammography, breast sonography for anatomic diagnostics and ¹⁸F-FDG whole body PET for functional one. But the PEM (Positron Emission Mammography) was developed to increase sensitivity, specificity and accuracy to improve the disadvantage of each study. Therefore this present study aims to describe availability of PEM for improving diagnosis of breast cancer. Materials and Methods: During 3 months from January in 2010, PEM was performed on 100 patients who had history of breast cancer. Using Naviscan’s PEM Flex Solo Ⅱ scanner, PEM images of breast were acquired. And then we evaluated sensitivity, specificity and accuracy of PEM data by comparing results of PEM images with postoperative pathologic finding. Results: On the 100 patients, it could reveal 89 true positive, 9 false positive, 7 false negative and 87 true negative. Thus the results of sensitivity, specificity and accuracy for PEM was evaluated 92.7%, 90.6% and 91.7%. Conclusion: The sensitivity, specificity and accuracy have been reported 83.7%, 68.5% and 77.1% in mammography, and that was 89.1%, 79.1% and 83.4% in breast sonography. However the results of PEM were more increased than others. Therefore the results of this study will be available that PEM used diagnosis with breast cancer, used preoperative operation plan and helps to discovery of a part recurrence.

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실험재료 및 방법

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키워드

PEM breast PET breast cancer imaging Sensitivity Specificity Accuracy