밤나무 노령목 전정처리가 결실 및 과실특성에 미치는 영향

• 영문명: Effects of Pruning on the Fruiting and Fruit Characteristics of Old Aged Chestnut
• 발행기관: 한국자원식물학회
• 저자명: 오성일(Oh, Sung-Il) 김창현(Kim, Chang-Hyun) 변시은(Byeon, Si-Eun) 김철우(Kim, Chul-Woo) 이욱(Lee, Uk)
• 간행물 정보: 『한국자원식물학회 학술심포지엄』2019년도 춘계학술대회, 114~114쪽, 전체 1쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2019.04.30

영문 초록

Arctium minus (AM), commonly known as lesser burdock, is a dried fruit (seed) of Aructium lappa L. that belong to Asteraceae. It has been used traditionally as herbal medicine because of its anti-inflammatory effects, and it has been applied to treat various diseases like allergies, skin aging, hyperlipidemia and urinary stone. In this study, we investigated the inhibitory effects of AM on the production of pro-inflammatory cytokines in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Pre-treatment of the RAW 264.7 cells with AM considerably inhibited and reduced production of Nitric Oxide (NO) and pro-inflammatory cytokines, such as interleukin (IL)-6 and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), and also shows suppression of nuclear factor-kappa B (NF-${\kappa}B$) translocation. In addition, AM treatment considerably reduced phosphorylation of mitogen-activated protein kinase (MAPK) in LPS-stimulated RAW 264.7 cells. Our results indicate that the AM has potential to inhibit inflammation through suppressing production of inflammatory mediators via both the NF-${\kappa}B$ and MAPK signaling pathway. We therefore suggest that AM might be effective therapeutics for the treatment of various inflammatory diseases.

키워드

Arctium minus inflammation LPS