스피루리나 플라텐시스에 의한 즉시형 과민반응의 억제효과

• 영문명: Inhibitory Effect of Immediate Hypersensitivity by Spirulina platensis
• 발행기관: 대한약학회
• 저자명: 김형민(Hyung Min Kim) 송호준(Ho Joon Song) 신민교(Min Kyo Shin) 신태용(Tae Yong Shin)
• 간행물 정보: 『약학회지』제41권 제5호 (1997년), 647~651쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1997.10.31

영문 초록

We studied the effects of the powders of Spirulina platensis (SPP) on anaphylactic reactions. SPP inhibited systemic anaphylaxis induced by compound 48/80 in rats. SPP also inhibited local anaphylaxis activated by anti-dinitrophenyl(DNP) IgE. Moreover, SPP dose-dependently inhibited histamine release in rat peritoneal mast cells activated by compound 48/80 or anti DNP-IgE. These results suggest that SPP may contain compounds with actions that inhibit mast cell degranulation in the rat.

키워드

Spirulina platensis Anaphylaxis Compound 48/80 Anti-dinitrophenyl(DNP)IgE Histamine Mast cells.