사철나무의 알칼로이드 성분

• 영문명: Sesquiterpene Pyridine Alkaloids from Euonymus japonica
• 발행기관: 대한약학회
• 저자명: 류재하(Jae Ha Ryu) 은진희(Jin Hee Eun) 이소영(So Young Lee) 장준식(Joon Shik Chang) 박만기(Man Ki Park) 박정일(Jeong Hill Park) 한용남(Yong Nam Han) 한병훈(Byung Hoon Han)
• 간행물 정보: 『약학회지』제41권 제5호 (1997년), 554~558쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1997.10.31

영문 초록

Two alkaloidal components were isolated from the ether soluble part of the MeOH extract of the root bark of Euonymus japonica. Their structures were elucidated by the spectroscopic analylses as the sesquiterpene pyridine alkaloids derived from polyester sesquiterpenes which are characteristically detected in Celastraceae plants. These include macrocycle formed by two ester linkages between dihydro-beta-agarofuran nucleus and pyridinic dibasic acid(compound 1:evoninic acid, compound 2:wilfordic acid). The structure of compound 1[C47H50N2017, mp 161~163oC. [alpha]D28=+31.6o(c, 0.1 in EtOH)] was determined as novel structure named as euojaponine N, and compound 2[C48H57NO18, mp 142~145oC, [alpha]D27=+27.0o(c, 0.1 in EtOH)] was identified as ebenifoline W-I reported from Maytenus ebenifolia.

키워드

Celastraceae alkaloids euojaponine N Euonymus japonica.