쓴맛이 차폐된 편자 고형엘릭실제의 제조 및 평가

• 영문명: Preparation and Evaluation of Coated-Peonja Dry Elixir for Masking the Bitterness
• 발행기관: 대한약학회
• 저자명: 김종국(Chong Kook Kim) 최한곤(Han Gon Choi)
• 간행물 정보: 『약학회지』제41권 제5호 (1997년), 602~606쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1997.10.31

영문 초록

Peonjahwan composed of crude herb, and materials and tissue of animals is a considerably bitter and poorly water-soluble oriental medicine for the treatment of hepatitis. Peonja dry elixir and Eudragit-coated peonja dry elixir were prepared using spray-dryer to mask the bitterness and enhance the release of ingredients from peonjahwan. The bitterness of peonja dry elixir and Eudragit-coated peonja dry elixir reduced to 1/2 and 1/4 of that from peonja powder, respectively. Furthermore, the release rate of bound bilirubin from dry elixir was significantly higher than that from peonja powder.

키워드

Peonjahwan Eudragit coated dry elixir Dry elixir Bitterness test.