PET/CT 에서 표준섭취계수(SUV)의 신뢰성 확보를 위한 초기연구

• 영문명: An Initial Study on the Reliability Assurance in PET/CT Standardized Uptake Values
• 발행기관: 대한핵의학기술학회
• 저자명: 박훈희(Hoon Hee Park) 김정열(Jung Yul Kim) 이승재(Seung Jae Lee) 박민수(Min Soo Park) 남궁혁(Hyuk NamKoong) 임한상(Han Sang Lim) 오기백(Ki Baek Oh) 김재삼(Jae Sam Kim) 이창호(Chang Ho Lee) 진계환(Gye Hwan Jin)
• 간행물 정보: 『핵의학기술』Vol.13 No.2, 31~42쪽, 전체 12쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2009.10.30

영문 초록

Purpose: As the number of domestic medical institutions installing PET/CT is increasing rapidly, the transfer of PET/CT images among medical institutions is also increasing. Thus, it is necessary to collect the comparative SUV data from several medical institutions’ PET/CT systems through a phantom study which semiquantitatively compares the SUV on one bed, the change scale of the SUV on the slices, and the time of measuring. The phantom study to find differences among the SUVs from various PET/CT offers the opportunity to obtain the reliability of the SUV in PET/CT images. Materials and Methods: Ten PET/CT systems from medical institutions in Korea were used. To obtain the accurate data, the study has been using the radiation detector of Korea Research Institute of Standards and Science to verify. The internal structures of NEMA PET phantom TM were removed and Six thousand milliliters of distilled water which has 1mCi of 18F-FDG put into the phantom. The water was properly integrated with 18F-FDG using magnetic stirrer. The images were acquired at 60, 70, 80, 90, 100, 110 and 120-minutes for 3 minute each. Two hundred square centimeters of region of interests were placed and analyzed. To confirm the usefulness, the correction-table came out from patients’ data. Results: The coefficient of variability of the SUV from -11.0 to 9.90 % fell into the range of international standards(±10%) along with the SUV on a bed, the change scale of the SUV on the slices, and the time of measuring, except one PET/CT system. Using the data of the differences among the SUVs, we came to withdraw the correction-table ranging from 0.803 to 1.246. The correction-table was confirmed its usefulness through Linear Regression Analysis which was applied to normal cases. Conclusions: Although studies have been made on the variation of the SUV, there is little attention on the standardization of the SUV. Based on this study of the quantitatively comparable data about the SUV accommodating the correction-table, it would help to have more corrective diagnosis.

목차

INTRODUCTION

MATERIALS AND METHODS

RESULTS

CONCLUSIONS

요약

REFERENCES

키워드

Nuclear medicine image PET/CT Quantization Standardized uptake value