참돌꽃 근경의 항산화작용

• 영문명: Antioxidative Effects of the Rhizome of Rhodiola Sachalinensis
• 발행기관: 대한약학회
• 저자명: 류광열(Kwang Youl Ryu) 강원식(Won Seek Kang) 김영호(Young Ho Kim) 장해동(Hae Dong Jang) 홍진태(Jin Tae Hong) 유환수(Hwan Soo Yoo) 윤여표(Yeo Pyo Yun)
• 간행물 정보: 『약학회지』제42권 제3호 (1998년), 312~318쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1998.06.30

영문 초록

Ihe purpose of this study was to determine the antioxidative effects of Rhodiola sachalinensis. Rhodiola methanol extract was fractionated sequentially with dichloromethane and butanol. Each Rhodiola fraction (water, MeOH, BuOH and CH2Cl2 fractions) showed the potent superoxide dismutase (SOD) activity, and had inhibitory effects on peroxide value of linoleic acid (40-57%) and lipid peroxidation (47-70%). In Fe2+/ascorbate system-induced rat liver microsome. Rhodiola methanol extract also recovered carbon tetrachloride-induced decrease in SOD by 42% and catalase activities by 50%, and had inhibitory effects (54%) on carbon tetrachloride-induced lipid peroxidation in rat liver microsome. These results suggest that Rhodiola sachalinensis has the antioxidative effects.

키워드

Rhodiola sachalinensis antioxidative effects superoxide dismutase catalase activity lipid peroxidation.