아연화의 최적 합성조건

• 영문명: Optimal Synthesis Conditions of Zinc White
• 발행기관: 대한약학회
• 저자명: 신화우(Wha Woo Shin) 김윤설(Youn Seol Kim)
• 간행물 정보: 『약학회지』제40권 제6호 (1996년), 659~665쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1996.12.31

영문 초록

Zinc white is mainly used as a mild astringent, protectant. and has weak antiseptic action. It is well known that the yield of zinc white produced is greatly affected by the synthetic conditions such as the reactant concentration, reaction temperature, washing water temperature, mole ratio of reactants, and drying temperature, calcination temperature, etc. The purpose of this study is to investigate the optimal synthesis conditions of zinc white produced. A randomized complete block design suggested by G.E.P. Box and K.B. Wilson was applied for this purpose. Basic zinc carbonate was prepared by reacting zinc sulfate and sod. carbonate solution in this study. Zinc white comes when prepared by calcination of basic zinc carbonate. The optimum synthesis conditions of zinc white obtained from this study is as follows: 1) The reacting temperature range is: 92-100oC, 2) The concentration of reactant solution is 23.6-27%. 3) The optimum mole-ratio: [ZnSO4]/[Na2CO3] is 1.74~1.96, 4) The washing water temperature is 36oC, 5) The drying temperature range is 68-74oC, 6) The calcination temperature is 600oC. The outcome of DSC indicated a desolvation of basic zinc carbonate occurred at about 133.3oC. The dehydration of the compound ceased at about 267.9oC and the decarboxylation ceased at about 379.9o. The physical and chemical properties of zinc white as medicine were studied by use of Volume Test.

키워드

Synthesis of zinc white Box-Wilson experimental design basic zinc carbonate DSC curves.