PET/CT 검사 시 혈관삽입기구 내 잔여 방사능 위치에 따른 표준섭취계수의 영향 비교 평가

• 영문명: Comparative Evaluation for the Effect of SUV’s Due to a Residual Radio-activity Location Inside Vascular Insert Devices During PET/CT Scans
• 발행기관: 대한핵의학기술학회
• 저자명: 심우용(Woo Yong Sim) 김정열(Jung Yul Kim) 조석원(Suk Won Cho) 오신현(Shin Hyun Oh) 임한상(Han Sang Lim) 박훈희(Hoon-Hee Park)
• 간행물 정보: 『핵의학기술』Vol.18 No.1, 94~97쪽, 전체 4쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2014.05.30

영문 초록

Purpose: Standardized uptake value (SUV) is a simple semi-quantitative method that can measure the ratio of the tissue radioactivity between the tumor and normal. SUV is commonly used in PET/CT, however, SUV is affected by various factor. The purpose of this study was to evaluate the impact of the residual activity on SUV depending on the location of catheter insertion device post injection. Materials and Methods: NEMA IEC Body Phantom was imaged using a Discovery 600 PET scanner. In 22 mm diameter sphere, the different activity of 18F-FDG (7.4, 14.8, 22.2, 29.6, 37, 55.5 MBq) was filled and background was filled with 18F-FDG (5.7 kBq/mL). We scaned the phantom on the assumption that the radioactivity in sphere was residual activity in insertion device. Simulation of PET was divided into three groups based on the location of sphere in Scan FOV (SFOV); inclusion, 1/2 inclusion and exclusion group. Results: Among three groups, the group of excluded sphere showed the highest SUV regardless of the amount of ¹⁸F-FDG activity. In case of 7.4 MBq, average SUV of inclusion group, 1/2 inclusion and exclusion group was 0.780, 0.840 and 0.896 respectively. However, average SUV of 55.5 MBq showed 0.372, 0.460 and 0.508 with same order. Depend on residual radioactivity in the sphere and position of sphere, the SUV was different minimum of 10.4%, maximum of 62.8%. Conclusion: This study showed that SUV is underestimated as the residual radio-activity is increased. In addition, SUV was a changed according to the position of residual radio-activity. And among the position, exclusion group showed the difference of SUV was lowest. If we measure the residual radio-activity of inserting devices and radio-activity from extra-vasation in the patients, it seems to be more useful in clinical field.

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실험재료 및 방법

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키워드

PET/CT Injection site SUV FOV