대황류생약의 혈소판응집억제작용

• 영문명: Effects of Rheum Plants on Blood Platelet Aggregation
• 발행기관: 대한약학회
• 저자명: 고성권(Sung Kwon Ko) 이승목(Seung Mok Lee) 황완균(Wan Kyunn Whang)
• 간행물 정보: 『약학회지』제43권 제2호 (1999년), 233~236쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1999.04.27

영문 초록

In order to clarify the anti-Ohyul activity of rhubarb, we investigated the effects of water extract from rhizomes of four different rhubarb on blood platelet aggregation induced by arachidonic acid, ADP, collagen and PAF in vitro. The cultivated Korean rhubarb rhizomes (Rheum undulatum) exhibited the most potent inhibitory action on the aggregation induced by arachidonic acid and also among the four fractions, stilbene components containing part showed strong inhibitory action. These inhibitory effect may partially contributed to anti-Ohyul activity of rhubarb.

키워드

Platelet aggregation Rheum undulatum cultivated Korean rhubarb rhizomes stilbene components.