복수암 생쥐에 대한 발효녹용의 항암작용

• 영문명: Antitumor Activity of Fermented Antler on Sarcoma 180 in Mice
• 발행기관: 대한약학회
• 저자명: 김동현(Dong Hyun Kim) 한상범(Sang Bum Han) 유기웅(Ki Ung Yu) 김유숙(Yu Suk Kim) 한명주(Myung Joo Han)
• 간행물 정보: 『약학회지』제38권 제6호 (1994년), 795~799쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1994.12.30

영문 초록

Some components and antitumor effect of antler and fermented antler with Bacillus P-92 were determined. By fermenting the antler with Bacillus P-92, the amount of free amino acids, polypeptides and other compounds were increased. The free amino acid of the fermented antler was 6-fold higher than those of the untreated antler. Sarcoma 180 cells were intraperitoneally implanted into ICR mice to determine the effect of fermented antler and untreated antler on life span prolongation. The life span of ICR mouse treated with antler and fermented antler were prolonged to 24.4% and 39.2%(p<0.05), and survival rates were 22% and 33%, respectively. In addtion, the induction of neutrophil was 2.3-fold and 3.4-fold, respectively.