D-1,3-Dioxolane 및 D-1,3-Oxathiolane 피리미딘 뉴크레오사이드의 합성

• 영문명: Synthesis of D-1,3-Dioxolane and D-1,3-Oxathiolane Pyrimidine Nucleosides
• 발행기관: 대한약학회
• 저자명: 홍준희(Joon Hee Hong) 차마리(Ma Rie Cha) 신성은(Seong Eun Shin) 최보길(Bo Gil Choi) 정병호(Byung Ho Chung) 김중협(Joong Huyup Kim) 이종교(Chong Kyo Lee) 정원근(Won Keun Chung) 천문우(Moon Woo Chun)
• 간행물 정보: 『약학회지』제38권 제6호 (1994년), 703~711쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1994.12.30

영문 초록

We synthesized D-1,3-dioxolanyl acetate from D-mannose using Frazer-Reide reaction and D-1,3-oxathiolanyl acetate from either D-mannose or D-galactose in good yields. These acetates were conjugated with various disilylated pyrimidine base using trimethylsilyl trifluoromethane sulfonate as a Lewis acid catalyst to obtain 32 different D-nucleosides.