지연성 운동장애의 유병율 및 위험인자 조사

• 영문명: A Study on the Prevalence and Risk Factors of Tardive Dyskinesia
• 발행기관: 대한신경정신의학회
• 저자명: 반철식 김영훈 심주철
• 간행물 정보: 『신경정신의학』제34권 제6호, 1585~1595쪽, 전체 11쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1995.11.30

영문 초록

We examined 423 chronic psychiatric inpatients who had a history of at least three months’ total cumulative neuroleptic exposure for tardive dyskinesia(TD). In this study, we used both structured scales of dyskinesia and videotape recording. Demographic, clinical, and drug history data were collected to assess whether any of these factors was significantly associated with TD. The authors found a high prevalence(51.3%) of TD. The subjects over age 60 are significantly associated with the presence of TD. Female sex, duration of hospitalization, length of neuroleptic treatment, and exposure to antiparkinsonian agents also were related to increased risk. However, there was no significant relationship between the presence of TD and other factors including psychiatric diagnosis, daily dosage of neuroleptics, or history of alcohol, smoking, electroconvulsive therapy, head trauma. Interestingly, the history of tricyclic antidepressant medication was associated with decreased prevalence. Further work is needed to perform well-controlled prospective study.

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키워드

Tardive dyskinesia Prevalence rate Risk factors