새로운 퀴놀론 항균제 DW-116의 Post-Antibiotic Effect

• 영문명: Post-Antibiotic Effect of DW-116, a New Quinolone
• 발행기관: 대한약학회
• 저자명: 최금화(Keum Hwa Choi) 오태권(Tae Kwon Oh) 백문창(Moon Chang Baek) 김병각(Byung Kak Kim) 최응칠(Eung Chil Choi)
• 간행물 정보: 『약학회지』제42권 제2호 (1998년), 229~231쪽, 전체 3쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1998.04.30

영문 초록

The post-antibiotic effects (PAE) of DW-116 were evaluated against Bacillus subtilis ATCC 6633, Bacillus cereus ATCC 27348, Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922 and Pseudomonas aeruginosa MB4-16, repectively. Against gram-positive bacteria, PAEs of DW-116 were longer duration (20-35 min) than those of rufloxacin(1O-20 min), and shorter than those of ciprofloxacin (50-90 min). Especially, against E. coli, DW-116 and ciprofloxacin obtained approximately 3 hrs of PAES.

키워드

Post-antibiotic effect(PAE) DW-116 rufloxacin ofloxacin.