상부 소화관 질환증상에 대한 제산, 소화효소 및 생약 세립의 유용성

• 영문명: Clinical Evaluation of Granules Containing Antacids, Digestive Enzymes and Herb Drugs in Patients with Various Symptoms of Upper Gastrointestinal Disorders
• 발행기관: 대한약학회
• 저자명: 구자영(Ja Young Koo) 박능화(Neung Hwa Park) 최종수(Jeong Soo Choi) 안수열(Soo Yeul Ahn)
• 간행물 정보: 『약학회지』제37권 제5호 (1993년), 520~526쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1993.10.30

영문 초록

The purpose of this study is to assess the clinical efficacy and safety of NRM granules which were newly developed as a combination product containing antacids, digestive enzymes and herb drugs for the treatmet of various symptoms of upper gastrointestinal disorders taking SGN granules of similiar but different composition as a control. One hundred and twenty one patients were randomly allocated to receive one pack of either NRM granule(80 cases) or SGN granules(41 cases) three times a day after meal and undergone symptomatic, endoscopic and clinical laboratory assessment before and after two weeks of treatment. The results were as follows; 1. All symptoms except anorexia showed improvements in more than 90% of total cases with each symptom in the NRM group. 2. The general improvement rate was 97.5% in NRM group, and was superior to the(92.5%) of SGN group. 3. Two cases of NRM group and one case of SGN group developed mild nausea, and onecase of SGN group developed mild epigastric soreness. No cases of the two groups developed laboratory(blood, biochemical, urine) abnormalities. 4. The overall clinical efficacy rate was 95.0% in NRM group, 87.8% in SGN group. According to the result of this trial, it was concluded that NRM granule was an effective and safe drug and(but not statistically significant) was slightly more efficient than SGN for treatment of various symptoms in upper gastrointestinal disorders.

키워드

NRM Clinical Gastrointestinal Disorders Antacids Digestive enzymes Herb SGN.