생쥐의 장내 미생몰로부터 새로운 슬포트란스훼라제 생산균의 분리

• 영문명: Isolation of Sulfotransferase Producing Bacteria from Mouse Intestinal Microflora
• 발행기관: 대한약학회
• 저자명: 김병택(Byung-Taek Kim) 김은하(Eun-Ha K im) 김동현(Dong-Hyun Kim)
• 간행물 정보: 『약학회지』제36권 제5호 (1992년), 455~459쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1992.10.29

영문 초록

Haemophilus K-12 producing novel sulfotransferase was isolated from mouce intestinal flora. The enzyme catalyzed the transfer of sulfate group from p-nitrophenylsulfate to phenolic compounds. The optimum medium condition for the sulfotransferase production was 0.2% sucrose, 1% yeast extract, Na2HP0 4 and 0.5% NaCl. The enzyme production was induced by donor substrate, but was not by acceptors. When p-nitrophenylsulfate was used as a donor substrate, 1-naphthol was best substrate, followed by phenol, p-acetaminophenol and tyramine.