L1210 세포에 대한 약용 식물의 세포독성 검색

• 영문명: Screening on Cytotoxicity of Medicinal Plants against L1210 Cell
• 발행기관: 대한약학회
• 저자명: 배기환(Ki Hwan Bae) 민병선(Byung Sun Min) 도동선(Dong Sun Do) 김남수(Nam Soo Kim) 양기종(Gi Jong Yang) 안병준(Byung Zun Ahn)
• 간행물 정보: 『약학회지』제36권 제5호 (1992년), 491~495쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1992.10.29

영문 초록

For the research of cytotoxic natural products, 50 medicinal plants were extracted with benzene and methanol, separately, and screened against L1210 cells. From the results(Table I), 6 samples showed cytotoxicity both in benzene and methanol extracts of 17 samples in benzene extracts and 3 samples in methanol extracts, respectively. Generally, the cytotoxicity exhibited high frequency (34%) in benzene extract but low frequency in methanol extract (6%), it meant that active cytotoxic components had less polarity. ED50 values less than 10mcg/ml were observed in 17 medicinal plants.