노루오줌 근경의 진통성분

• 영문명: Analgesic Components of the Rhizoma of Astilbe chinensis var. davidii
• 발행기관: 대한약학회
• 저자명: 오갑진(Kap Jin Oh) 최윤석(Yun Seuk Choi) 최일식(Il Shik Choi) 박시경(Si Kyung Park) 이규흥(Kyou Heung Lee) 정순간(Sun Gan Chung) 조의환(Eui Hwna Cho)
• 간행물 정보: 『약학회지』제36권 제5호 (1992년), 474~480쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1992.10.29

영문 초록

Astilbes rhizoma has been used for headache, arthralgia, chronic bronchitis and stomachalgia in traditional chinese medicine. The analgesic activities and their components of Astilbe chinensis var. davidii Rhizomes were evaluated. The ether and ethylacetate fractions of 70% EtOH extract showed considerable analgesic activities by acetic acid induced writhing method. Compound 1~5 were isolated from ethylacetate fraction and identified as gallic acid, (+)-catechin, (+)-gallocatechin, bergenin and 11-O-galloylbergenin on the basis of spectroscopic methods. Among them (+)-gallocatechin showed stronger analgesic activity than that of other compounds.