급성 파종성 뇌척수염(Acute Disseminated Encephalomyelitis) 1례

• 영문명: A Case of Acute Disseminated Encephalomyelitis
• 발행기관: 대한소아신경학회
• 저자명: 이진수(Lee Jin Soo) 이준수(Lee Jun Soo) 고창준(Coe Chang Joon)
• 간행물 정보: 『Annals of Child Neurology(구 대한소아신경학회지)』대한소아신경학회지 제2권 제1호, 191~199쪽, 전체 9쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 1994.12.20

영문 초록

Acute disseminated encephalomyelitis(ADEM), an acute or subacute inflammatory demyelinating disease of the central nervous system, cause lesions in white matter. Since viral infection. vaccination, or upper respiratory infection frequently precedes the disease, it is also called as postinfectious encephalomyelitis, postvaccinial encephalomyelitis, postvaccinial leukoencephalitis. The pathophysiology is thought to be an autoimmune nature, mainly involving the myelin sheath, and one third of the encephalitis patients are known to develop the disease, more frequent in children than in adults. As the clinical manifestations or laboratory findings is nonspecific ti is difficult to differentiate from acute viral encephalitis, bacterial encephalitis and other demyelinating disease by computed tomography. Therfore it requires to get T2 weighted image by magnetic resonance imaging to diagnoses by the monophasic high signal intensity. It well known to respond high-dose steroids. As the mortality is 10-30% in acute phase, but in most of cases symptom improves in a few weeks to months. However, neurological deficits may be left sometimes. As the magnetic resonance imaging technique is becoming popular. it has reported frequently in recent days. The authors experienced a case on a child who had hand-foot-mouth disease 2 weeks before, had visual difficulty. convulsion and deteriorated into comatous state by the time of his hospitalizations. The patient was diagnosed as acute disseminated encephalomyelitis by magnetic resonance imaging, who was recovered from the disease.

키워드

ADEM demyelinating white matter MRI