동적 신장 신티그래피 검사 시 사용되는 Gates 법과 Modified Gates 법의 사구체 여과율 비교에 관한 고찰

• 영문명: A Study on Glomerular Filtration Rate Comparisons between Gates Method and Modified Gates Method used in Dynamic Renal Scintigraphy
• 발행기관: 대한핵의학기술학회
• 저자명: 함준철(Jun Cheol Ham) 반영각(Young Kag Bahn) 박민수(Min Soo Park) 조석원(Seok Won Cho) 임한상(Han Sang Lim) 김재삼(Jae Sam Kim) 이창호(Chang Ho Lee)
• 간행물 정보: 『핵의학기술』Vol.16 No.1, 96~101쪽, 전체 6쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2012.04.30

영문 초록

Purpose: Glomerular filtration rate is an important index for assessment of renal function, early discovery of renal disease, and progress observation of chronic renal disease patients. In the present study, the objective is to conduct a comparative analysis of differences between Gates and Modified Gates method in dynamic renal scintigraphy based on MDRD (Modification of Diet Renal Disease) formula using blood collection. Materials and Methods: Renal scintigraphy was performed for 45 patients who visited our hospital between November 2010 and August 2011. For 20 patients of those tested, glomerular filtration rates from Gates method and MDRD formula using AGUS equipment, were compared. For the other 20 patients, glomerular filtration rates from Modified Gates method and MDRD formula using INFINIA equipment. Finally, Gates and Modified Gates method were compared for 5 patients who indicated no change in glomerular filtration rates from MDRD formula during progress observation. Results: Glomerular filtration rates from both Gates and Modified Gates method showed a high correlation with those from MDRD formula (p<0.01, r=0.903, r=0.867), with a paired difference mean for Gates method of 2.05±2.54 mL/min/1.73 m, and that for Modified Gates method of 25.2±3.71 mL/min/1.73 m. Finally, the values for Gates method and those for Modified Gates method showed a high correlation for the five patients (p<0.05, r=0.949), with a paired difference mean of 20.4±8.84 mL/min/1.73 m. Conclusion: Glomerular filtration rates from Gates method, Modified Gates method and MDRD formula showed mutually high correlations. If the tests are performed with recognition for the correlations between Gates and Modified Gates method used in a dynamic renal scintigraphy, then an accurate assessment of renal function is considered possible with an improved diagnostic ability.

목차

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대상 및 방법

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키워드

Renal scintigraphy Gates method Modified Gates method MDRD (Modification of Diet Renal Disease)