대추로부터 베튜리닉 산과 알피톨릭 산의 분리 및 정량

• 영문명: Isolation and Quantitative Analysis of Betulinic Acid and Alphitolic Acid from Zyziphi Fructus
• 발행기관: 대한약학회
• 저자명: 배기환(Ki Hwan Bae) 이상명(Sang Myung Lee) 이은실(Eun Sil Lee) 이준성(Jun Sung Lee) 강종성(Jong Seong Kang)
• 간행물 정보: 『약학회지』제40권 제5호 (1996년), 558~562쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1996.10.31

영문 초록

Betulinic acid and alphitolic acid, the triterpenoids of Zyziphi Fructus, were isolated with silica gel column chromatography and used as the standard substances for the analysis. The compounds were determined with HPLC and HPTLC. They were separated on reversed phase column (Nova-Pak C18) with 0.05M Na2HPO4-methanol (19:81) in HPLC and detected at 210nm. Separation on HPTLC precoated silica gel F254 plates was carried out with chloroform-methanol (6:1) and the separated compounds were reacted with p-anisaldehyde and detected at 540nm. The contents of betulinic acid and alphitolic acid in Zyziphi Fructus from four different regions in Korea were in the range of 2.9~3.8% and 3.2~3.9%, respectively.

키워드

Zyziphi Fructus betulinic acid alphitolic acid HPLC HPTLC.