인삼의 diol계 사포닌으로부터 새로운 배당체 (20E)-Ginsenoside Rh3 및 그의 입체이성체의 제조와 구조 결정

• 영문명: Preparation and Structure Determination of a New Glycoside, (20E)-Ginsenoside Rh3, and its isomer from Diol-type Ginseng Saponins
• 발행기관: 대한약학회
• 저자명: 김동선(Dong Seon Kim) 백남인(Nam In Baek) 박종대(Jong Dae Park) 이유희(You Hui Lee) 정소영(So Young Jeong) 이천배(Chun Bae Lim) 김신일(Shin Il Kim)
• 간행물 정보: 『약학회지』제39권 제1호 (1995년), 85~93쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1995.02.28

영문 초록

Acidic and alkaline hydrolysis of diol-type ginseng saponins produced a new glycoside, (20E)-ginsenoside Rh3, and its stereoisomer (20Z)-, which were further subjected to alkaline hydrolysis to give their aglycones, (20E)- and (20Z)-3beta, 12beta-dihydroxy-dammar-20(22),24-diene. The ratio of stereoisomeric mixtures was estimated to be ca. 5 : 1 from intensities of the peaks in 1H- and 13C-NMR spectra. The 1H- and 13C-NMR signals of ginsenoside Rh3, which have remained unclarified, were completely assigned by the extensive application of modern NMR techniques.