카바프로스타싸이클린 중간체의 합성: 1-Alkoxy-benzenesulfonyl-cyano-4-ethenyl cyclopeptane의 입체선택적 합성

• 영문명: Synthesis of an Intermediate for Carbaprostacyclin: Stereoselective Synthesis of 1-Alkoxy-3-benzenesulfonyl-3-cyano- 4-ethenyl cyclopentane
• 발행기관: 대한약학회
• 저자명: 서영거(Young Ger Suh) 정재경(Jae Kyoung Jung) 구본암(Bon Am Koo) 최영기(Young Gi Choi) 조윤상(Youn Sang Cho)
• 간행물 정보: 『약학회지』제39권 제1호 (1995년), 41~47쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1995.02.28

영문 초록

An efficient and stereoselective synthetic route to the trisubstituted hydroxy cyclopentane as an useful synthetic intermediate for carbaprostacyclin is described. Pd(O)-mediated intramolecular alkylation of allylic carbonate has been employed as a key reaction.