7,8번 위치에 이중결합을 갖는 10-membered lactone의 효율적인 합성

• 영문명: Efficient Synthesis of 10-Membered Lactone Possessing Ring-olefin at 7,8-Position
• 발행기관: 대한약학회
• 저자명: 서영거(Young Ger Suh) 이지연(Jee Yeon Lee) 조윤상(Youn Sang Cho)
• 간행물 정보: 『약학회지』제39권 제1호 (1995년), 31~35쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1995.02.28

영문 초록

An unusual 10-membered lactone possesing ring-olefin at 7,8-position has been efficiently synthesized. The w-hydroxy acid as a cyclization precusor was derived from epsilon-caprolactone in 41% overall yield of 7 steps and efficiently cyclized by Mukaiyama procedure.