수종동물의 췌장조직내 NO Synthase 활성도 및 Methylarginiies 함량

• 영문명: NO Synthase Activities and Methylarginines Contents in the Pancreatic Tissues of Various Animals
• 발행기관: 대한약학회
• 저자명: 김용기(Yong Kee Kim) 박승희(Seung Hee Park) 남석우(Suk Woo Nam) 서동완(Dong Wan Seo) 홍성렬(Sung Youl Hong) 이향우(Hyang Woo Lee)
• 간행물 정보: 『약학회지』제38권 제2호 (1994년), 184~190쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1994.04.30

영문 초록

The activities of nitric oxide synthase and the contents of methylarginines were inves-tigated in the pancreatic tissues of various animals by citrulline-forming method and HPLC, respectively. The high level of in vitro NO synthase activity was detected in chicken pancreas whereas MMA, the strong competitive inhibitor for NO synthase, was detected as trace in the same tissue. On the other hand, the low level of NO synthase activity was observed in the porcine pancreas while the contents of MMA were high. However, it was not possible to find any relationship between NO synthase activities and the contents of dimethylarginines at present time. DMA was equally distributed among the pancreatic tissues of various animals but DMA was not.