Benign Epilepsy of Childhood with Centrotemporal Spikes

• 영문명: Benign epilepsy of childhood with centrotemporal spikes : Short term prognosis and prognostic factor
• 발행기관: 대한소아신경학회
• 저자명: 박원일(Wonil Park) 한상주(Sang Ju Han) 이홍진(Hong Jin Lee) 이경자(Kyung Ja Lee)
• 간행물 정보: 『Annals of Child Neurology(구 대한소아신경학회지)』대한소아신경학회지 제1권 제2호, 74~81쪽, 전체 8쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 1993.12.20

영문 초록

Objective. To identify the short-term prognostic factor, and also assess the clinical and EEG changes following treatment. Patient and Method. We reviewed the medical record of 24 patient who followed up more than 12month, and compared seizure control rate as a pedictor according to sex, age at onset, seizure type, ferequency. BECCT was diagnosed as following criteria: 1) nocturnal seizures or hemifacial seizure on wakening state, 2) normal intelligence and no abnormal neurologic sign, 3) normal EEG background activity with monomorphic sharp or spike acticity which increase the frequence during sleep if sleep EEG was available. Result. 1) Age at onset was range from 3 years to 11 years (7.1±1.9) and Patient were followed up from 12 month to 92 months.(34.8±25.1) 2) Seizure was free in 54.2% of patients 1 month after therapy, in 75.0% 6 month after, in 83.3% 1 year after, in 95.8% 2 year after. We found that seizure frequence before treatment was the most important predictor ( P < 0.05 ), and also found that male, older age at onset had more fovorable outcome of prognosis during follow up. 3) Partial seizures were increased from 54.2% before therapy to 83.2% after therapy and seizure pattern tend to become localized to the face.( P < 0.05). 4) Epileptiform discharge did not disappear from the EEG during short-term follw up. Conclusion. Although BECCT recurred frequently during short-term follow, BECCT has not only an excellent long term prognosis bu also mild seizure localized to the face following treatment. It would be better to avoid heavy dose of AED or polytherapy, and we found the age onset, frequence of seizure as predictor of the seizure relapse.

키워드

BECCT predictor