흡연 및 비흡연 정신분열증환자의 정신병적 증상과 약물 부작용에 관한 비교 연구

• 영문명: A Comparative Study of Smoking and Nonsmoking Schizophrenics with Respect to Psychotic Symptoms and Medication Side Effects
• 발행기관: 대한신경정신의학회
• 저자명: 이종학 배성일 이택희
• 간행물 정보: 『신경정신의학』제34권 제1호, 50~58쪽, 전체 9쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1995.01.30

영문 초록

This study was designed to investigate the effects of smoking on schizophrenics by comparing smoking and nonsmoking schizophrenics in terms of the doses of antipsychotics, psychotic symptoms and medication side effects, especially parkinsonism and dyskinetic movement, using BPRS (Brief Psychiatric Rating Scale) and ESRS (Extrapyramidal Symptom Rating Scale). The results were as follows : 1) A statistically significant difference has been found in the doses of antipsychotics at the time of the research ; calculated in terms of chlorpromazine equivalent, the daily mean was 883.53± 498.66mg in the case of smokers, 637.88± 314.03mg in the case of non-smokers. 2) As for BPRS, no statistically significant difference has been found in total score between smokers and nonsmokers. Significant difference has not been found in subscales such as depressive mood, tension, anxiety and excitement 3) In the parkinsonism subscale of ESRS, the mean was 3.55士 2.74 in the case of smokers and 7.85±4.73 in the case of nonsmokers showing a statistically significant difference. 4) In the dyskinetic movement subscale of ESRS, the mean was 0.83 士 0.94 in the case of smokers, 1.41 士 1.63 in the case of non-smokers, showing no statistically significant difference. Summerizing the above results, the dose of antipsychotics was significantly higher in smokers and parkinsonism was significantly lower in smokers. However, the total score of BPRS and dyskinetic movement of ESRS have not shown significant differences between smokers and non smokers.

목차

서 론

연구 대상 및 방법

결 과

고 찰

요 약

참 고 문 헌

키워드

Smoking Schizophrenia Antipsychotic drug Parkinsonism Tardive dyskinesia Dyskinetic movement