强迫障碍와 人間組織適合性抗原

• 영문명: Obsessive Compulsive Disorder and Histocompatibility Antigen
• 발행기관: 대한신경정신의학회
• 저자명: 姜秉肺 元勝喜 秋東销
• 간행물 정보: 『신경정신의학』제34권 제1호, 5~14쪽, 전체 10쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1995.01.30

영문 초록

A HLA-typing(HLA-A，B, C , D R , D Q ) was conducted on 35 patients diagnosed as obsessive compulsive disorder(OCD) based on the DSM-IH-R criteria for a comparison with HLA of the normal controls. The normal controls consisted of 30 healthy medical students for HLAA, B, C and 136 healthy persons for HLA-DR, DQ. The Tearasaki method was used for HLA-A, B，C and PCR method, for HLA-DR, DQ. The frequencies of HLA for both OCD patients and the normal controls were compared by means of the Gart and Nam statistical analysis method and the Pvalue was corrected by multiplying the tested antigen numbers, to avoid the Type 1 error. When compared with the normal controls, HLA-B60 was found significantly high in frequencies among OCD patients(p

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키워드

Obsessive compulsive disorder HLA Genetic marker

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