電氣衝擊이 白鼠의 線條體内 도파민 受容體에 미치는 影響

• 영문명: Effect of Electroconvulsive Shock (ECS) on Dopamine Receptors in the Rat Corpus Striatum
• 발행기관: 대한신경정신의학회
• 저자명: 김진수 김용식 이정균 박주배
• 간행물 정보: 『신경정신의학』제24권 제1호, 12~17쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1985.02.28

영문 초록

For the purpose of examining the nature of certain psychiatric illnesses on which ECS has some beneficial effect authors observed the effect of ECS on striatal dopamine receptors of male albino Sprague-Dawley rats,: divided into twelve groups according to three factors-treatment (ECS， sham-ECS and control), frequency (one time and seven times) and maturity (interval between decapitation and the last treatment). The result is： there was no significant difference between groups. Through the finding .of Jip difference between sham-ECS and control groups we can exclued the possible relationship of nonspecific stress effects induced by sham-ECS with the ECS-induced effect The finding that there was nd significant difference between ECS and control groups was discussed carefully in view of inappropriateness of experimental model. Further well-controlled researches are needed to examine the delayed effect of ECS.

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