선택적 레이저 섬유주성형술의 장기임상효과와 성공예측인자의 분석

• 영문명: Long-Term Outcomes and Predictive Factors for Success of Selective Laser Trabeculoplasty
• 발행기관: 대한안과학회
• 저자명: 이지영 이유경 문정일 박명희,Ji Young Lee, MD, You Kyung Lee, MD, Jung Il Moon, MD, PhD, Myoung Hee Park, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume55,number9, 1347~1354쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.09.15

영문 초록

Purpose: To investigate long-term outcomes and predictive success factors for selective laser trabeculoplasty (SLT). Methods: This retrospective chart review included 66 eyes of 66 glaucoma or ocular hypertension patients who underwent SLT between 2004 and 2011. All patients were followed-up for at least 2 years after the procedure. The intraocular pressure (IOP) was measured before the treatment, at postoperative 1 week, 1 month and every 3 months thereafter. Success was defined as an IOP decrease ≥ 3 mm Hg or ≥ 20% of the pretreatment IOP. The success rate was determined based on the Kaplan-Meier survival analysis. The predictive success factors were analyzed using the Cox proportional hazard model. Results: The mean follow-up period was 4.78 ± 1.98 (2-8) years. The mean pretreatment IOP was 23.79 ± 2.83 mm Hg. The mean IOP reduction was 6.64 ± 3.21 mm Hg. The success rates were 80%, 75%, 69%, 63%, 50%, 45%, and 42% after 1, 2, 3, 4, 5, 6, and 7 years, respectively. Only high pretreatment IOP was significantly correlated with success (p = 0.044). Conclusions: SLT was an effective tool for lowering IOP in glaucoma patients. Higher pretreatment IOP was a predictive success factor. J Korean Ophthalmol Soc 2014;55(9):1347-1354

키워드

Glaucoma, Intraocular pressure, Predictive factor, Selective laser trabeculoplasty (SLT), Success rate