비삼출성 나이관련황반변성 환자와 정상인의 망막신경섬유층 두께 비교

• 영문명: Comparison of Retinal Nerve Fiber Layers in Patients with Non-Neovascular Age-Related Macular Degeneration and Normal Controls
• 발행기관: 대한안과학회
• 저자명: 김재영 정혜원 김형찬,Jae Young Kim, MD, Hyewon Chung, MD, PhD, Hyung Chan Kim, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume55,number9, 1334~1339쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.09.15

영문 초록

Purpose: In neovascular age-related macular degeneration (AMD), it is reported that retinal nerve fiber layer (RNFL) thickness becomes gradually thinner due to degeneration of the outer retinal layer. To our knowledge, there is no previous report regarding RNFL thickness in patients with non-neovascular AMD. Therefore, in this study, we compared RNFL thickness in patients with non-neovascular AMD and normal controls. Methods: Thirty-one eyes with AMD category 3a (AREDS research group), 11 eyes suffering foveal geographic atrophy AMD category 4a, and 31 age-matched normal eyes were evaluated. In every group, regional RNFL thickness (General, Temporal, Superotemporal, Superonasal, Superior, Nasal, Inferonasal, Inferotemporal, and Inferior) was measured using spectral domain optical coherence tomography (SD-OCT). Results: There were no significant differences in age or intraocular pressure among the 3 groups. The mean best corrected visual acuity (BCVA) (log MAR) of the category 4a group was significantly decreased compared to those of the other 2 groups. The mean RNFL thickness in total area in the category 3a group, category 4a group, and normal control group was 99.5 ± 14.0 μm, 99.3 ± 9.4 μm, and 99.4 ± 9.6 μm, respectively. The difference was not statistically significant. No other regional mean values of RNFL thickness in the three groups were significantly different. Conclusions: There was no significant difference in RNFL thickness between non-neovascular patients and the control group. J Korean Ophthalmol Soc 2014;55(9):1334-1339

키워드

Non-neovascular age-related macular degeneration, Retinal nerve fiber layer thickness, Spectral domain optical coherence tomography