굴절교정레이저각막절제술 후 트라닐라스트의 각막혼탁 억제에 대한 펜타캠을 이용한 분석

• 영문명: Effects of Topical Tranilast on Corneal Haze with the Pentacam; after Photorefractive Keratectomy
• 발행기관: 대한안과학회
• 저자명: 김성인 오태훈,Sung In Kim, MD, Tae Hoon Oh, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume55,number9, 1277~1283쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.09.15

영문 초록

Purpose: To evaluate the inhibitory effect of tranilast on formation of corneal haze using the Pentacam^{Ⓡ after photorefractive keratectomy (PRK). Methods: A prospective, randomized, paired eye study was performed. A total of 60 eyes from 30 patients were enrolled in the present study. Eyes were categorized as myopic eyes <-5 D and ≥-5 D. Patients undergoing PRK were randomized to receive tranilast in one eye and no medication in the contralateral eye. Three months postoperatively, corneal haze was measured with the PentacamⓇand compared between the 2 groups. Results: Statistical differences were not found in preoperative data in the tranilast or control groups (all p > 0.05). There was a strong decreasing density trend from the apex to the 3 mm radius in both groups (p < 0.05). However, postoperative corneal haze in the tranilast group was similar to the control group (p > 0.05). Conclusions: The use of tranilast after PRK did not inhibit corneal opacity. Additionally, PentacamⓇ can provide a useful objective measure of corneal haze. J Korean Ophthalmol Soc 2014;55(9):1277-1283}

키워드

Corneal haze, Pentacam PRK, Tranilast