Methyl Orange에 의한 4급 Amine류의 Ion Pair 유출 흡광도 정량(I) Cetyltrimethylammonium bromide, Bretylium tosylate, Gallamine triethiodide 및 Thiamine의 정량

• 영문명: Spectrophotometric Determination of Ion Pair Extraction of Quaternary Amines with Methyl Orange
• 발행기관: 대한약학회
• 저자명: 최종환(Jong Hwan Choi) 김영수(Young Soo Kim)
• 간행물 정보: 『약학회지』제31권 제2호 (1987년), 45~51쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1987.04.30

영문 초록

Methyl orange(MO) and cetyltrimethylammonium bromide(CTA) were mixed and added to 10ml of the buffer solution and then the solution was shaken for 5 minutes. The maximum absorption wavelength of the reaction product was 419nm. Dichloromethane was the best extracting solvent among the several organic solvents and the most suitable pH range was 2-8. When the CTA-MO calibration curve was made in the best experimental condition, the Lambert-Beer''s law was obeyed in the range of CTA concentration of 1.5 X 10-5-1.0 X 10-4M by UV spectrophotometer. This method was possible to determine quaternary ammonium salts in the pharmaceutical preparations.