새로운 beta-락탐계 물질의 합성 및 그 항균력

• 영문명: Synthesis and Antibacterial Activities of New beta-Lactam Compounds
• 발행기관: 대한약학회
• 저자명: 진정일(Jung Il Jin) 장민선(Min Sun Chang) 민신홍(Shin Hong Min)
• 간행물 정보: 『약학회지』제30권 제6호 (1986년), 294~300쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1986.12.30

영문 초록

New antibiotics having moieties of penicillanic acid, cephalosporanic acid and ampicillin on both ends of the central polyalkylene were synthesized by reacting 6-aminopenicillanic acid (6-APA1), 7-amino cephalosporanic acid (7-ACA) and ampicillin with hexamethylene diisocyanate and sebacoyl chloride, respecetively. Antibiacterial activities of the compounds were also investigated.