2차 미분 자외부 분광광도법에 의한 정제중의 아세트아미노펜 정량

• 영문명: Determination of Acetaminophen in Tablet Formulations by Second Derivative Ultraviolet Spectrometry
• 발행기관: 대한약학회
• 저자명: 유경수(Gyurng Soo Yoo) 고익배(Ik Bae Koh)
• 간행물 정보: 『약학회지』제30권 제2호 (1986년), 100~103쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1986.04.30

영문 초록

The second derivative absorption spectra of acetaminophen in commercial tablet forms were measured without prior separation from other pharmaceutical adjuvants. The second derivative spectra of acetaminophen were found to have no influence on the characteristic absorbance band of it. A plot of 25 sets of the ordinate (Z) values with various acetaminophen concentrations mixed in other additives gave a straight line (correlation coefficient, 0.9999) and the slope was 2.901 X 1O-2Z value/(mcg/ml). The procedures were sufficiently sensitive, precise and economical for the assay of tablets of acetaminophen.