Purine 대사과정에 미치는 마늘 수침액의 영향

• 영문명: Effect of Garlic on the Purine Metabolic Pathway
• 발행기관: 대한약학회
• 저자명: 허근(Keun Huh) 이상일(Sang Il Lee) 박종민(Jong Min Park) 김석환(Suk Hwan Kim)
• 간행물 정보: 『약학회지』제30권 제2호 (1986년), 62~67쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1986.04.30

영문 초록

It was attempted to observe the effect of garlic on the hepatic purine metabolizing enzymes in this study. The activities of adenosine deaminase, guanase, and uricase in rats were not changed significantly following the feeding of 5% garlic juice. Whereas, garlic juice inhibited significantly the hepatic xanthine oxidase activity compared to control group with the lapse of treated-period. The urate level of serum in rats was significantly decreased by the treatment of garlic juice. The above inhibitory effect of garlic was greater in boiled garlic juice than fresh garlic juice-treated group. These results indicated that, according to the chemical properties of allicin which is unstable in heat, other components than allicin in garlic may regulate the hepatic purine metabolizing enzymes.