Sodium 5-Methoxy Salicylate의 흡수촉진 효과에 관한 연구(II) 흡수촉진제에 대한 반응성

• 영문명: A Study on the Absorption Enhancing Effect of Sodium 5-Methoxysalicylate(II) -On the Activity of the Absorption Enhancing Agent-
• 발행기관: 대한약학회
• 저자명: 김기헌(Ki Heun Kim)
• 간행물 정보: 『약학회지』제30권 제2호 (1986년), 96~99쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1986.04.30

영문 초록

Absorption enhancing effect of 5MSA-Na at the mucous membranes of the rectum and duodenum was studied via in vitro sac test. There were no significant differences between two membranes. Effect of 5MSA-Na on the transfer of CMZ to the tissue was also studied via in situ loop method. There was no significant difference at the duodenum, compared to the control when CMZ was administered intravenously. Transfer of CMZ to the loop of the rectum was increased in the presence of 5MSA-Na compared to the control, which might be attributed to the enhanced permeability of the mucous membrane of the rectum.