한국 성인의 헤모글로빈 당화지수와 대사증후군 위험요인 간의 연관성

• 영문명: Association between Hemoglobin Glycation Index and Metabolic Syndrome Risk Factors in Korean Adults
• 발행기관: 한국보건기초의학회
• 저자명: 신경아
• 간행물 정보: 『한국보건기초의학회지』제16권 제2호, 175~181쪽, 전체 7쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2023.12.31

국문 초록

The hemoglobin glycation index (HGI) is an index used to explain the difference between estimated and measured values of glycated hemoglobin (hemoglobin A1c). This study aimed to investigate the association between HGI and metabolic syndrome risk factors in Korean adults aged 20 years or older. This cross-sectional study targeted 4,431 people who underwent health checkups at the general health checkup center of ageneral hospital in the Gyeonggi area from June 2018 to May 2020. HGI was calculated by subtracting the predicted HbA1c from the measured HbA1c. In women, the prevalence of metabolic syndrome was 3.1% higher in the high HGI group than in the low HGI group (p=0.009), but in men there was no difference between groups. As a result of logistic regression analysis, HGI did not show a significant association with the development of metabolic syndrome, but an increase in HGI in men was found to reduce the risk of increased blood pressure by 33.8% (95% confidence level, 0.538-0.815, p<0.001). HGI was not found to be a more useful indicator than fasting blood sugar and HbA1c for diagnosis of metabolic syndrome. Therefore, it was unlikely to be used as an alternative indicator for predicting metabolic syndrome.

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키워드

Fasting glucose Hemoglobin A1c Hemoglobin glycation index Metabolic syndorme