A Rare Intraoperative PTH Level Spike Immediately After Parathyroid Resection: A Case of an Additional Adenoma

• 발행기관: 대한내분비외과학회
• 저자명: Haseeb E. Goheer Dylan M.N. Flood Jessica G. Wright Madaliene E. Denison Kristin L. McCoy David LeBel Kenneth M. Algino Michael S. Nussbaum
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』24권4호, 129~134쪽, 전체 6쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2024.12.31

국문 초록

Primary hyperparathyroidism is a frequent cause of hypercalcemia resulting from one or more parathyroid adenomas. We report the case of a 66-year-old female who underwent parathyroidectomy, during which intraoperative parathyroid hormone (ioPTH) levels spiked tenfold, from 197 pg/mL to 2,209 pg/mL, 10 minutes post-resection. Despite recalibration and re-sampling, ioPTH levels further increased to 3,000 pg/mL at 1 hour, prompting additional exploration and resection of a second adenoma. The patient’s serum calcium levels subsequently returned to normal postoperatively. This case highlights the importance of considering additional parathyroid adenomas in patients with unexpected spikes in ioPTH levels and underscores the need for thorough exploration rather than attributing such rises solely to laboratory error.

목차

INTRODUCTION

CASE REPORT

DISCUSSION

REFERENCES

키워드

Parathyroid glands Parathyroid adenoma Parathyroidectomy Parathyroid hormone