Thermotherapy as an alternative to exercise for metabolic health in obese postmenopausal women: focus on circulating irisin level

• 영문명: Thermotherapy as an alternative to exercise for metabolic health in obese postmenopausal women: focus on circulating irisin level
• 발행기관: 대한생리학회-대한약리학회
• 저자명: Seung-Jea Lee Tae-Wook Kim Tae-Hwan Park In-Ho Lee Eun-Chul Jang Soon-Chan Kwon Hye-Jin Lee
• 간행물 정보: 『The Korean Journal of Physiology & Pharmacology』제26권 제6호, 501~509쪽, 전체 9쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2022.11.30

영문 초록

Irisin is a myokine caused by exercise that improves insulin resistance and weight loss. However, under unfavorable conditions such as air pollution, and during the pandemic, outdoor activities are uncomfortable. Therefore, in this study, the effect of heat therapy (half bath 42 ± 0.5°C for 30 min) on irisin circulation levels as an exercise alternative for middle-aged obese women after menopause was investigated. Subjects were 33 women aged 49.54 ± 6.04 years, with parameters of height, 160.12 ± 4.33 cm, weight, 69.71 ± 7.52 kg, body surface area 1.73 ± 0.13 m2, body mass index, 27.19 ± 3.40 kg/m2. The results suggest that circulating irisin levels showed a significant increase after one-time thermotherapy (TH-1). However, the increase in circulating irisin levels after 15 treatments (TH-15, 5 days/week, 3 weeks) was significantly varied. The level of adiponectin, which increases fatty oxidation to reduce fatty deposition, increased significantly at TH-1, but further increased at TH- 15, which was significantly different from the level of TH-1. In addition, the basic serum free fatty acid (FFA) level was significantly increased at TH-15 compared to TH-1. Significant differences were also found in the lipid profile (body mass index, waist circumference, and % body fat). Thermotherapy can significantly increase the tympanic temperature and induce changes in circulating irisin and adiponectin levels. Thus, it resulted in positive changes in FFA and lipid profiles. Therefore, repeated thermotherapy is effective in increasing circulating irisin levels in postmenopausal obese women.

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INTRODUCTION

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ACKNOWLEDGEMENTS

CONFLICTS OF INTEREST

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REFERENCES

키워드

Adiponectin Free fatty acid Half bath Irisin Thermotherapy