학술논문
Regional Beta Index of Electroencephalography May Differentiate Alzheimer’s Disease from Depression
이용수 10
- 영문명
- 발행기관
- 대한신경정신의학회
- 저자명
- Kanghee Lee JiWon Han KiWoong Kim
- 간행물 정보
- 『Psychiatry Investigation』제14권 제5호, 708~711쪽, 전체 4쪽
- 주제분류
- 의약학 > 정신과학
- 파일형태
- 발행일자
- 2017.09.30
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국문 초록
영문 초록
Differentiating early Alzheimer’s disease (AD) from depression with cognitive impairment is challenging in the elderly. To develop a model for differentiating these two conditions using electroencephalography (EEG), we enrolled 11 patients with early probable AD and 11 age- and cognitive function-matched patients with major depressive disorder (MDD) and compared the EEG relative powers of 9 scalp regions. Compared to the MDD group, the AD group had a higher global theta relative power (p=0.021). In the MDD group, beta relative power was higher in the mid-central region than in the left or right central regions (p<0.01). The prediction model that included global theta relative power and regional beta index was able to discriminate AD from MDD (AUC=0.893, p=0.002). A combination of global theta relative power and intra-individual regional differences in beta may differentiate early AD from MDD with cognitive impairment.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
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