Periodic Limb Movements in Sleep is Associated with Increased Mortality

• 발행기관: 대한신경정신의학회
• 저자명: JaeWon Choi JiSoo Song YuJin Lee DoUn Jeong
• 간행물 정보: 『Psychiatry Investigation』제14권 제5호, 669~673쪽, 전체 5쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2017.09.30

영문 초록

Objective-To elucidate the association between periodic limb movements in sleep (PLMS) and mortality. Methods-Nocturnal polysomnographic recordings of 1,344 subjects obtained from 1995 to 2008 were reviewed. The subjects were divided into four groups based on PLMS and insomnia: reference group (PLMS≤5), insomnia group (PLMS≤5 with insomnia symptoms), 515 group. We searched each subject’s Identification Number in the death records from the Statistics of Korea, the national bureau of statistics, to determine deaths in the cohort that occurred prior to December, 2013. Cox-proportional hazard regression and Kaplan-Meier survival curve analyses were used to compare mortality among the four groups. Results-Hazard ratios (HRs) in the 515 groups were significantly higher than that in the reference group before adjusting for age and gender [HR, 3.37; 95% confidence interval (CI), 1.73–6.55; p<0.001; HR, 5.77; 95% CI, 3.24–10.29; p<0.001]. Only the PLMS>15 group had a higher mortality rate than that in the reference group after adjusting for age, gender, and sleep efficiency (HR, 1.99; 95% CI, 1.06–2.21; p=0.033). Conclusion-These results suggest that PLMS may be associated with increased mortality.

목차

INTRODUCTION

METHODS

RESULTS

DISCUSSION

REFERENCES

키워드

Periodic limb movements in sleep Mortality