소아 핵의학 검사 시 사용되는 방사성의약품의 양 산출 기준 조사

• 영문명: A Research of Standards for Radiopharmaceutical Doses in Pediatric Nuclear Medicine
• 발행기관: 대한핵의학기술학회
• 저자명: 도용호(Yong Ho Do) 김계환(Gye Hwan Kim) 이홍재(Hong Jae Lee) 김진의(Jin Eui Kim) 김현주(Hyun Joo Kim)
• 간행물 정보: 『핵의학기술』Vol.13 No.1, 47~50쪽, 전체 4쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2009.05.30

영문 초록

Purpose: Presently, any exact standard of radiopharmaceutical doses in pediatric nuclear medicine doesn’t exist in the universe. So hospitals are following by manual of vial kit or guidelines of America and Europe based on recommended adult doses adjusted for body mass (MBq/kg) or body surface area (MBq/m2). However, especially for children younger than 1 year and heavier than 50 kg, it’s hard to estimate exact dosage for those children. Materials and Methods: In order to obtain objective data of multipliers for pediatric studies, we surveyed 4 major hospitals in Korea. After receiving feedbacks, we changed dosage to multiplier. And we compared multipliers of Korea to America’s and Europe’s. Results: Most hospitals in Korea are following by body mass formula (MBq/kg). On the other hand, standards don’t include proper factors for a child younger than 1 year and heavier than 50 kg. Multipliers for 3 kg children who are injected lower doses than needed are America:0.12, Europe:0.09, Korea:0.05, multipliers for 30 kg children who are injected proper doses are America:0.58, Europe:0.51, Korea:0.45 and multipliers for 60 kg children who are injected more doses than needed are America:0.95, Europe:0.95, Korea:0.91. Conclusions : Through the survey, when calculating doses for children, usually output doses are based on adult doses adjusted for body mass (MBq/kg) but research has shown that standards of all of the compared standards don’t reflect exact multipliers for children younger than 1 year and heavier than 50 kg. Therefore, we should give an effort to reduce needless radiation exposure in children by establishing a proper doses standard and also developing better image reconstruction software.

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실험재료 및 방법

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REFERENCES

키워드

Pediatric nuclear medicine Radiopharmaceutical doses Multiplier