설견초와 병풀 추출물의 미백활성

• 영문명: Whitening Activities of Extracts of Salvia plebeia R. BR and Centella asiatica
• 발행기관: 한국인체미용예술학회
• 저자명: 임현지(Hyun-Ji Lim) 이해진(Hea-Jin Lee) 곽종복(Jong-Bok Kwak) 임미혜(Mi-Hye Lim)
• 간행물 정보: 『한국인체미용예술학회지』제25권 제1호, 79~87쪽, 전체 9쪽
• 주제분류: 예술체육 > 예술일반
• 파일형태: PDF
• 발행일자: 2024.03.20

영문 초록

This study attempted to assess the whitening activities of Salvia plebeia R. Br. and Centella asiatica extracts which were provided by MEIDEME CO., LTD., their safety was confirmed through cell viability testing. The whitening activities were evaluated by inhibition of melanin synthesis and reduction of whitening-related transcription factors and protein production. The results found that no statistically significant cytotoxicity was observed at 10㎍/㎖, 20㎍/㎖and 40㎍/㎖. In addition, melanin production decreased by 28.4% at Salvia plebeia R. BR and Centella asiatica extract(SCE) 40㎍/㎖. In transcription factors, tyrosinase, tyrosianse related protein(TRP-1) and dopachrome tautomerase(TRP-2) decreased by 17%, 21% and 22% respectively at SCE 40㎍/㎖, confirming statistical significance. Protein production also showed statistically significant results with decrease in tyrosinase, TRP-1 and TRP-2 by 87%, 40% and 27% each at SCE 40㎍/㎖. The above results confirm that SCE is effective in promoting whitening and would be available as a cosmetic ingredient for whitening cosmetics.

목차

Ⅰ. 서론

Ⅱ. 본론

Ⅲ. 결과 및 고찰

Ⅳ. 결론

키워드

설견초 병풀 멜라닌감소 기능성화장품 미백활성 Salvia plebeia R. BR Centella asiatica Melanin Reduction Functional Cosmetics Whitening Activity