학술논문
Genetically determined alcohol consumption and cancer risk in Korea
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- 영문명
- Genetically determined alcohol consumption and cancer risk in Korea
- 발행기관
- 한국역학회
- 저자명
- Keum Ji Jung Ji Woo Baek Sang Yop Shin Sun Ha Jee
- 간행물 정보
- 『Epidemiology and Health』45, 1~7쪽, 전체 7쪽
- 주제분류
- 의약학 > 면역학
- 파일형태
- 발행일자
- 2023.01.01
4,000원
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국문 초록
영문 초록
OBJECTIVES: The purpose of this study was to determine the causal relationship between the genetically determined amount of alcohol consumption and the occurrence of major cancers.
METHODS: The data used in this study were from 129,324 people selected from the Korean Cancer Prevention Study-II, the participants of which visited 18 health examination centers between 2004 and 2013. Cancer incidence was confirmed as of 2020 using data from the National Cancer Center. A genome-wide association study (GWAS) on alcohol consumption was performed using PLINK 2.0, and sex, age, chip type, and principal components were adjusted.
RESULTS: From the GWAS, a genetic risk score for alcohol consumption was calculated and genetically determined alcohol consumption (GDAC) was estimated. GDAC was divided into quintile groups and showed significant causal relationships with rectal cancer and liver cancer, but not with other cancers. For liver cancer, an association was shown in the hepatitis B surface antigen (HBsAg)-negative group, and a particularly strong association was found in the over-60-year-old HBsAg-negative group, in which, compared to the GDAC Q1 group, the Q4 group had a 2.35 times higher risk (95% confidence interval [CI], 1.05 to 5.23), and the Q5 group had a 2.40 times higher risk (95% CI, 1.09 to 5.30).
CONCLUSIONS: The results of this study provided evidence that the amount of alcohol consumed is causally related to the occurrence of rectal cancer and liver cancer in HBsAg-negative individuals. Additional studies should be continued for other cancer types through long-term follow-up.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
CONFLICT OF INTEREST
FUNDING
ACKNOWLEDGEMENTS
AUTHOR CONTRIBUTIONS
ORCID
REFERENCES
해당간행물 수록 논문
- Changes in health behaviors and obesity of Korean adolescents before and during the COVID-19 pandemic: a special report using the Korea Youth Risk Behavior Survey
- Higher energy consumption in the evening is associated with increased odds of obesity and metabolic syndrome: findings from the 2016-2018 Korea National Health and Nutrition Examination Survey (7th KNHANES)
- Regional disparities in major cancer incidence in Korea, 1999-2018
- Changes in proteinuria and the associated risks of ischemic heart disease, acute myocardial infarction, and angina pectoris in Korean population
- Risk of lymphadenopathy from SARS-CoV-2 vaccination in Korea: a self-controlled case series analysis
- Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis
- Association between PM2.5 exposure and risk of Parkinson’s disease in individuals with chronic obstructive pulmonary disease in Taiwan: a nested case-control study
- Forecasting the effects of vaccination on the COVID-19 pandemic in Malaysia using SEIRV compartmental models
- The physical activity paradox in relation to work ability and health-related productivity loss in Korea
- Limiting the spillover of zoonotic pathogens from traditional food markets in developing countries and a new market design for risk-proofing
- Age-specific findings on lifestyle and trajectories of cognitive function from the Korean Longitudinal Study of Aging
- Evidence integration on health damage for humidifier disinfectant exposure and legal presumption of causation
- Risk factors for early-onset lung cancer in Korea: analysis of a nationally representative population-based cohort
- Interaction between vitamin E intake and a COMT gene variant on colorectal cancer risk among Korean adults: a case-control study
- Association between cardiac arrhythmia before pregnancy and gestational diabetes: a nationwide population-based study in Korea
- Performance pressure and mental health among finance workers in Korea: a cross-sectional study
- Clinical severity according to the primary infection variant in patients with suspected SARS-CoV-2 reinfection in Korea
- Decreased birth weight after prenatal exposure to wildfires on the eastern coast of Korea in 2000
- Age at first childbirth and the risk of hypertriglyceridemia among Korean women
- Changes in mental health of Korean adolescents before and during the COVID-19 pandemic: a special report using the Korea Youth Risk Behavior Survey
- Trends in socioeconomic inequalities in obesity among Korean adolescents: the Korea Youth Risk Behavior Web-based Survey (KYRBS) 2006 to 2020
- Evaluation of an air quality warning system for vulnerable and susceptible individuals in Korea: an interrupted time series analysis
- The associations of tobacco use, sexually transmitted infections, HPV vaccination, and screening with the global incidence of cervical cancer: an ecological time series modeling study
- Clinical traits and systemic risks of familial diabetes mellitus according to age of onset and quantity: an analysis of data from the community-based KoGES cohort study
- Trends and all-cause mortality associated with multimorbidity of non-communicable diseases among adults in the United States, 1999-2018: a retrospective cohort study
- Outbreak of carbapenem-resistant Enterobacterales at a long-term care facility in Seoul, Korea: surveillance and intervention mitigation strategies
- Association of multiple anthropometric indices with in 944,760 elderly Chinese people
- Prediction of the 10-year risk of atherosclerotic cardiovascular disease in the Korean population
- Associations of cumulative average dietary total antioxidant capacity and intake of antioxidants with metabolic syndrome risk in Korean adults aged 40 years and older: a prospective cohort study (KoGES_CAVAS)
- Socioeconomic inequality in organized and opportunistic screening for colorectal cancer: results from the Korean National Cancer Screening Survey, 2009-2021
- Trends in the effects of socioeconomic position on physical activity levels and sedentary behavior among Korean adolescents
- Overall and cause-specific mortality in patients with dementia: a population-based cohort study in Taiwan
- Body mass index and prevalence of metabolic syndrome among Korean adults before and after the COVID-19 outbreak: a retrospective longitudinal study
- Does the father’s job matter? Parental occupation and preterm birth in Korea
- Genetically determined alcohol consumption and cancer risk in Korea
- Parental intention to vaccinate daughters with the human papillomavirus vaccine in Korea: a nationwide cross-sectional survey
- Aedes aegypti container preference for oviposition and its possible implications for dengue vector surveillance in Delhi, India
- Did the socioeconomic inequalities in avoidable and unavoidable mortality worsen during the first year of the COVID-19 pandemic in Korea?
- Adherence to the World Cancer Research Fund/American Institute for Cancer Research and Korean Cancer Prevention Guidelines and cancer risk: a prospective cohort study from the Health Examinees-Gem study
- The association between glaucoma and all-cause mortality in middle-aged and elderly Chinese people: results from the China Health and Retirement Longitudinal Study
- Exploring cognitive trajectories and their association with physical performance: evidence from the China Health and Retirement Longitudinal Study
- Effects of multigrain rice and white rice on periodontitis: an analysis using data from the Korea National Health and Nutrition Examination Survey 2012-2015
- Food literacy and its relationship with food intake: a comparison between adults and older adults using 2021 Seoul Food Survey data
- Non-linear relationship between body mass index and self-rated health in older Korean adults: body image and sex considerations
- Cancer incidence among male construction workers in Korea: a standardized incidence ratio analysis, 2009-2015
- Effect of trajectory of employment status on all-cause mortality in the late middle-aged and older population: results of the Korea Longitudinal Study of Aging (2006-2020)
- The Korea National Disability Registration System
- A comparison of methods for the measurement of adherence to antihypertensive multidrug therapy and the clinical consequences: a retrospective cohort study using the Korean nationwide claims database
- Changes in metabolic syndrome and the risk of breast and endometrial cancer according to menopause in Korean women
- Epidemiological investigation of a food-borne outbreak in a kindergarten, Jeju Province, Korea
- Risk of cancer, cardiovascular disease, thromboembolism, and mortality in patients with rheumatoid arthritis receiving Janus kinase inhibitors: a real-world retrospective observational study using Korean health insurance data
- Associations of breastfeeding duration and the total number of children breastfed with self-reported osteoarthritis in Korea women 50 years and older: a cross-sectional study
- The associations of obesity phenotypes with the risk of hypertension and its transitions among middle-aged and older Chinese adults
- Estimated trends in hospitalizations due to occupational injuries in Korea based on the Korean National Hospital Discharge In-depth Injury Survey (2006-2019)
- Association of group-level segregation with cardiovascular health in older adults: an analysis of data from the Korean Social Life, Health, and Aging Project
- Detecting mpox infection in the early epidemic: an epidemiologic investigation of the third and fourth cases in Korea
- No association between genetically predicted C-reactive protein levels and colorectal cancer survival in Korean: two-sample Mendelian randomization analysis
- Disease burden of prostate cancer from 2014 to 2019 in the United States: estimation from the Global Burden of Disease Study 2019 and Medical Expenditure Panel Survey
- The association of dietary patterns with incident chronic kidney disease and kidney function decline among middle-aged Korean adults: a cohort study
- Chronic obstructive pulmonary disease mortality trends in Spain, 1980-2020
- Impact of statin treatment on cardiovascular events in patients with retinal vein occlusion: a nested case-control study in Korea
- Changes in mental health service utilization before and during the COVID-19 pandemic: a nationwide database analysis in Korea
- Physical activity, sedentary behavior, and cardiovascular disease risk in Korea: a trajectory analysis
- Long-term association of pericardial adipose tissue with incident diabetes and prediabetes: the Coronary Artery Risk Development in Young Adults Study
- The association between occupational stress level and health-related productivity loss among Korean employees
- Associations between digital media use and lack of physical exercise among middle-school adolescents in Korea
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