국내 류마티스 관절염의 처방 현황 분석

• 영문명: Analysis of Prescription Patterns for Rheumatoid Arthritis in Korea
• 발행기관: 대한약학회
• 저자명: 김윤숙(Yoonsook Kim) 천부순(Pusoon Chun)
• 간행물 정보: 『약학회지』제63권 제6호(2019년), 341~350쪽, 전체 10쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2019.12.30

영문 초록

This study was conducted to analyze the prescription patterns of glucocorticoids and disease-modifying antirheumatic drugs (DMARDs) in the management of rheumatoid arthritis. A cross-sectional study was conducted using the claims data of the Health Insurance Review and Assessment Service-National Patient Samples-2016. A total of 4,147 patients were analyzed. About 38, 28, and 6% received triamcinolone, methylprednisolone, and hydrocortisone, whereas 65, 45, 30, and 20% received methotrexate, hydroxychloroquine, leflunomide, and sulfasalazine. A total of 369 patients received biological DMARDs and approximately 47% received tocilizumab or adalimumab. Most of the biological DMARDs were concurrently prescribed with synthetic DMARD, especially methotrexate. In case of injectable glucocorticoids, 84% of the repeated injections were given within 12 weeks after the previous injections. As for oral glucocorticoid cases, 48% were “low dose” and stopped within 3 months. Furthermore, 15% continued for more than 6 months and 20% were prescribed at high doses. This study found that the prescription patterns of DMARDs met with the guidelines of American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR). However, in many cases of glucocorticoid uses, the dose was higher and the duration was longer than the recommendations of the guidelines. High doses and longterm use of glucocorticoids should be restrained to prevent serious side effects.

목차

서 론(Introduction)

연구방법(Research Methods)

결 과(Results)

고 찰(Discussion)

결 론(Conclusion)

감사의 말씀(Acknowledgment)

Conflict of Interest

References

키워드

Disease-modifying antirheumatic drugs glucocorticoids prescription patterns rheumatoid arthritis